I spoke to Paul at Vienna and he felt there is issue with Cube 7, Vienna is always upfront with any issue so I am believing his statement as VEP5 in Cubase 6.5 works perfectly. Please let me know what information I can provide to further diagnose and let me know if there are any known issue with VEP5 and Cubase See below for the setup I am using, I have tried on both Motu and Steinberg MR816 audio interface to eliminate that as issue.